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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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ChIP-Seq of yeast to survey transcription factor binding sites

ABSTRACT: An experiment was performed to determine the transcription factor binding site of yeast at room temperature.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Bryan Venters

PROVIDER: E-MTAB-440 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces.

Venters Bryan J BJ Wachi Shinichiro S Mavrich Travis N TN Andersen Barbara E BE Jena Peony P Sinnamon Andrew J AJ Jain Priyanka P Rolleri Noah S NS Jiang Cizhong C Hemeryck-Walsh Christine C Pugh B Franklin BF

Molecular cell 20110201 4

Hundreds of different proteins regulate and implement transcription in Saccharomyces. Yet their interrelationships have not been investigated on a comprehensive scale. Here we determined the genome-wide binding locations of 200 transcription-related proteins, under normal and acute heat-shock conditions. This study distinguishes binding between distal versus proximal promoter regions as well as the 3' ends of genes for nearly all mRNA and tRNA genes. This study reveals (1) a greater diversity an ...[more]

PMID: 21329885

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