Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

RNA-Seq of Schistosoma mansoni (flatworms) larva and adult individuals at different life-stages

ABSTRACT: High-throughput sequencing of life stages and tissues of the flatworm Schistosoma mansoni to be used for further gene editing, gene finding and transcriptome analysis

INSTRUMENT(S): Illumina Genome Analyzer II

ORGANISM(S): Schistosoma mansoni

SUBMITTER: Anna Protasio

PROVIDER: E-MTAB-451 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.

Protasio Anna V AV Tsai Isheng J IJ Babbage Anne A Nichol Sarah S Hunt Martin M Aslett Martin A MA De Silva Nishadi N Velarde Giles S GS Anderson Tim J C TJ Clark Richard C RC Davidson Claire C Dillon Gary P GP Holroyd Nancy E NE LoVerde Philip T PT Lloyd Christine C McQuillan Jacquelline J Oliveira Guilherme G Otto Thomas D TD Parker-Manuel Sophia J SJ Quail Michael A MA Wilson R Alan RA Zerlotini Adhemar A Dunne David W DW Berriman Matthew M

PLoS neglected tropical diseases 20120110 1

Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people in developing countries. Amongst the human-infective species, Schistosoma mansoni is also the most commonly used in the laboratory and here we present the systematic improvement of its draft genome. We used Sanger capillary and deep-coverage Illumina sequencing from clonal worms to upgrade the highly fragmented draft 380 Mb genome to one with only 885 scaffolds and more than 81% of the bases organised i ...[more]

PMID: 22253936

Dataset Information

RNA-Seq of Schistosoma mansoni (flatworms) larva and adult individuals at different life-stages

Publications

A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.

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