Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of peripheral blood mononuclear cells from individuals after treatment with fish oil containing EPA/DHA or high oleic acid sunflower oil


ABSTRACT:

ORGANISM(S): Homo sapiens

SUBMITTER: Guido Hooiveld 

PROVIDER: E-MTAB-48 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.

Bouwens Mark M   van de Rest Ondine O   Dellschaft Neele N   Bromhaar Mechteld Grootte MG   de Groot Lisette C P G M LC   Geleijnse Johanna M JM   Müller Michael M   Afman Lydia A LA  

The American journal of clinical nutrition 20090610 2


<h4>Background</h4>Polyunsaturated fatty acids can have beneficial effects on human immune cells, such as peripheral blood mononuclear cells (PBMCs). However, the mechanisms of action of polyunsaturated fatty acids on immune cells are still largely unknown.<h4>Objective</h4>The objective was to examine the effects of supplementation with the polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on whole-genome PBMC gene expression profiles, in healthy Dutch elder  ...[more]

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