Transcriptome profiling of glioblastoma biopsies obtained by neuro-navigation in four distinct areas for 10 patients (necrotic zone, tumor zone, interface, and peripheral brain zone).

ABSTRACT: We classified samples and deciphered a key genes signature of intratumor heterogeneity by Principal Component Analysis and Weighted Gene Co-expression Network Analysis. Transcriptome analysis highlighted a pronounced intratumor architecture reflecting the surgical sampling plan of the study and identified gene modules associated with hallmarks of cancer.

ORGANISM(S): Homo sapiens

SUBMITTER: Amandine Etcheverry 

PROVIDER: E-MTAB-5092 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress