Proteotranscriptomic view on the role of spider silk glands during the silk spinning process

ABSTRACT: Spider silk proteins are synthesized in the silk-producing glands, where the spidroins are produced, stored and processed into a solid fiber from a crystalline liquid solution. Despite great interest in the spider silk properties, that make this material suitable for biomedical and biotechnological applications, the mechanism of formation and spinning of the silk fibers has not been fully elucidated; and no combination of proteomic and transcriptomic study has been carried out so far in the spider silk-producing glands. Nephila clavipes is an attractive orb-web spider to investigate the spinning process of silk production, given the properties of strength, elasticity and biocompatibility of their silk fibers. Thus, considering that the combination of proteomic and transcriptomic analysis m

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Nephila clavipes

SUBMITTER: Thomas Nussbaumer 

PROVIDER: E-MTAB-5451 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress