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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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ChIP-on-chip of Sgs1 and gammaH2A and DNA:RNA hybrids in wild type and SGS1 mutants

ABSTRACT: Sgs1 is a DNA helicase with roles in DNA replication and repair. DNA repair proteins have been linked to genome instability in part by altering the landscape of DNA:RNA hybrids. Here, we mapped the Sgs1 binding profile along with the profile of DNA:RNA hybrids and gammaH2A genome-wide in an effort to identify direct vs indirect effects of Sgs1 in DNA:RNA hybrid and gammaH2A distribution. The wild type DNA:RNA hybrid sample was reported previously in E-MTAB-2388.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Maria Aristizabal

PROVIDER: E-MTAB-5582 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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