Digital Karyotyping for Detecting Chromosome Alterations

ABSTRACT: To establish a method for calling digital karyotypes using the Illumina HumanCoreExome BeadChip, we calculated the percent of cells within a population that were required to detect a chromosome alteration. We performed serial dilutions of an iPSC line with Trisomy 12, 13, 14, 17, 20, and XXY and a genetically matched clone. Dilutions were at 0, 6.25, 12.5, 25 and 50% abnormal cells.

ORGANISM(S): Homo sapiens

SUBMITTER: Kelly Frazer 

PROVIDER: E-MTAB-5587 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress