RNA-Seq of CD19+ B-cell populations from patients with juvenile dermatomyositis and controls

ABSTRACT: RNA sequencing was used to compare the transcriptional state of ex-vivo B-cells from children with Juvenile dermatomyositis (JDM) pre- and on-treatment and age-matched healthy controls. RNA was extracted from blood samples that were taken from juvenile dermatomyositis patients at diagnosis (before they received treatment) and approximately a year into treatment. The treatment included oral prednisolone, methotrexate, azathioprine, cyclophosphamide and other drugs.

INSTRUMENT(S): NextSeq 500, FACSAria III

ORGANISM(S): Homo sapiens

SUBMITTER: Georg Otto 

PROVIDER: E-MTAB-5616 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress