Transcriptome analysis of self-renewing human pancreatic progenitors derived from pluripotent stem cells

ABSTRACT: Human pluripotent stem cells were differentiated into PDX1+/NKX6-1+ Pancreatic Progenitors (PPd15 cells), which were subsequently captured and expanded in culture. These culture Pancreatic Progenitors (cPP cells) were capable of self-renewal and could be passaged up to 20 times. Furthermore, cPP cells were capable of differentiation into multiple pancreatic lineages, including c-peptide+ beta-like cells, both in vitro and in vivo.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo sapiens

SUBMITTER: Jamie Trott 

PROVIDER: E-MTAB-5731 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress