Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Genetic control of yeast chromatin acetylation epi-polymorphisms


ABSTRACT: Genetic control of yeast chromatin acetylation epi-polymorphisms

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Gael Yvert 

PROVIDER: E-MTAB-575 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genetic modifiers of chromatin acetylation antagonize the reprogramming of epi-polymorphisms.

Abraham Anne-Laure AL   Nagarajan Muniyandi M   Veyrieras Jean-Baptiste JB   Bottin Hélène H   Steinmetz Lars M LM   Yvert Gaël G  

PLoS genetics 20120920 9


Natural populations are known to differ not only in DNA but also in their chromatin-associated epigenetic marks. When such inter-individual epigenomic differences (or "epi-polymorphisms") are observed, their stability is usually not known: they may or may not be reprogrammed over time or upon environmental changes. In addition, their origin may be purely epigenetic, or they may result from regulatory variation encoded in the DNA. Studying epi-polymorphisms requires, therefore, an assessment of t  ...[more]

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