The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity

ABSTRACT: Upon perturbations by RAS and by shBMAL, differential effects on the circadian phenotype were observed in wild type and Ink4a/Arf knockout MEFs which could be reproduced by modelling simulations and correlated with opposing cell cycle fate decisions.

ORGANISM(S): Mus musculus

SUBMITTER: Angela Relógio 

PROVIDER: E-MTAB-5943 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress