Differential gene expression study in brain samples from patients suffering distinct frontotemporal lobar degeneration (FTLD) conditions.

ABSTRACT: RNA extracted from human frontal cortex area 8, the main area afected in FTLD, of controls (n=10), sporadic FTLD-TDP (sFTLD) (n=10) and C9ORF72-familial FTLD (fFTLD) (n=10) samples were analyzed using the Affymetrix Clariom™ D Assay, human (Affymetrix ref.902923). The present study identifies the main gene deregulation between sporadic forms of FTLD-TDP (sFTLD) and the major and most common genetic cause of FTLD, the C9ORF72 repeat expansion (fFTLD), when compare with control samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Pol Andrés Benito 

PROVIDER: E-MTAB-6189 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress