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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging

ABSTRACT: Beige fat is specialized for energy expenditure and has therefore been proposed to function as a defense against obesity. The loss of beige fat is associated with the age-dependent decline in metabolism. In this study, we isolated a subpopulation of adipogenic progenitors (Sca-1+/CD45−/Mac1−; referred to as Sca- 1+ progenitor cells, ScaPCs) residing in subcutaneous white fat from young and aged mice to determine the gene signature of aging.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Kosaku Shinoda

PROVIDER: E-MTAB-6502 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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