Transcriptomic effects of long-term pantethine treatment in the mouse Alzheimer's disease 5XFAD model

ABSTRACT: Pantethine, an anti-cholesterol drug, was shown to inhibit the Ab (amyloid beta) peptide-induced expression of IL-1b in primary culture astrocytes derived from either untreated Ab-treated and untreated 5XFAD or Ab-treated WT. These observations prompted us to investigate the effects of pantethine at the transcriptomic level in the mouse AD model.

ORGANISM(S): Mus musculus

SUBMITTER: Philippe Benech 

PROVIDER: E-MTAB-6772 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress