Microarray data from YTHDF2-deficient pre-leukemic cells and control pre-leukemic cells

ABSTRACT: YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To study the role of YTHDF2 in leukemia, c-Kit+ cells from foetal livers of Ythdf2fl/fl;Vav-iCre (Ythdf2CKO) and Ythdf2fl/fl (Ythdf2CTL) 14.5 dpc embryos were transduced with Meis1 and Hoxa9 oncogenes and serially re-plated to generate pre-leukemic cells. Total RNA from Ythdf2CKO (n=5) and Ythdf2CTL (n=5) pre-leukemic cells were used for Affymetrix global gene expression analysis.

ORGANISM(S): Mus musculus

SUBMITTER: Marcos Morgan 

PROVIDER: E-MTAB-6783 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress