Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Group B meningococcus (M1239) - Wild type and M2-D strains grown at mid log in GC broth and stressed with 100uM dipyridil


ABSTRACT: Analysis of global transcription profile of wild type M1239 and M2-D strains grown at mid log in GC broth until mid log phase and stressed with 100uM dipyridyl

ORGANISM(S): Neisseria meningitidis

SUBMITTER: Laura Fantappi 

PROVIDER: E-MTAB-687 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Identification of the in vitro target of an iron-responsive AraC-like protein from Neisseria meningitidis that is in a regulatory cascade with Fur.

Fantappiè Laura L   Scarlato Vincenzo V   Delany Isabel I  

Microbiology (Reading, England) 20110520 Pt 8


In this study we characterized a genetic locus that is predicted to encode one of the three AraC-like regulators of Neisseria meningitidis, a homologue of MpeR of Neisseria gonorrhoeae which is specific to the pathogenic Neisseria species. Previous microarray studies have suggested that this gene is a member of the Fur regulon. In strain MC58, it is a pseudogene (annotated as two ORFs, NMB1879 and NMB1878) containing a frameshift mutation which we show is common to all strains tested belonging t  ...[more]

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