Genes differentially expressed in MLL-AF9-transduced versus HOXA9/MEIS1-transduced LSK cells

ABSTRACT: HOXA9 and MEIS1 are essential downstream effectors of the MLL-AF9 oncoprotein during leukaemia induction. Leukaemia derived from MLL-AF9-transduced LSK cells has a more aggressive phenotype than that derived from HOXA9/MEIS1-transduced LSK cells. To determine differential gene expression that contributes to increased aggressiveness in MLL-AF9-induced leukaemia, microarray was performed on LSK cells transduced with MLL-AF9 versus HOXA/MEIS1 oncogenes.

ORGANISM(S): Mus musculus

SUBMITTER: Jenny Wang 

PROVIDER: E-MTAB-7355 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress