Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Maria Rossing
PROVIDER: E-MTAB-736 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Rossing Maria M Borup Rehannah R Henao Ricardo R Winther Ole O Vikesaa Jonas J Niazi Omid O Godballe Christian C Krogdahl Annelise A Glud Martin M Hjort-Sørensen Christian C Kiss Katalin K Bennedbæk Finn Noe FN Nielsen Finn Cilius FC
Journal of molecular endocrinology 20120125 1
The molecular determinants of thyroid follicular nodules are incompletely understood and assessment of malignancy is a diagnostic challenge. Since microRNA (miRNA) analyses could provide new leads to malignant progression, we characterised the global miRNA expression in follicular adenoma (FA) and follicular carcinoma (FC). Comparison of carcinoma and adenoma with normal thyroid revealed 150 and 107 differentially expressed miRNAs respectively. Most miRNAs were down-regulated and especially miR- ...[more]