Microarray of heads of embryonic day (E) 9 mouse embryos, irradiated with 1-Gy X-rays at E7.5 compared to 0-Gy controls

ABSTRACT: Exposure to ionizing radiation around the time of neural tube closure results in a number of developmental defects, including neural tube defects (e.g. exencephaly, cleft palate) and eye defects (e.g. microphtalmos, anaphtalmos). These defects result from perturbed neural tube closure and development of the presumptive eye. In order to better understand the underlying molecular mechanisms, gene expression profiling was performed in heads of mouse embryos at embryonic day 9, after they had been irradiated at embryonic day 7.5 with 1 Gy of X-rays. Non-irradiated mice served as controls for differential gene expression.

ORGANISM(S): Mus musculus

SUBMITTER: Roel Quintens 

PROVIDER: E-MTAB-7532 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress