Transcription profiling of yeast grown in a three-factor design to study the relationship between specific growth rate and genome-wide gene expression
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Alessandro Fazio
PROVIDER: E-MTAB-78 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Transcription factor control of growth rate dependent genes in Saccharomyces cerevisiae: a three factor design.
Fazio Alessandro A Jewett Michael C MC Daran-Lapujade Pascale P Mustacchi Roberta R Usaite Renata R Pronk Jack T JT Workman Christopher T CT Nielsen Jens J
BMC genomics 20080718
<h4>Background</h4>Characterization of cellular growth is central to understanding living systems. Here, we applied a three-factor design to study the relationship between specific growth rate and genome-wide gene expression in 36 steady-state chemostat cultures of Saccharomyces cerevisiae. The three factors we considered were specific growth rate, nutrient limitation, and oxygen availability.<h4>Results</h4>We identified 268 growth rate dependent genes, independent of nutrient limitation and ox ...[more]
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