RNA-seq of blood samples from bovines immunized with a multicomponent recombinant vaccine against cattle tick.

ABSTRACT: Tick infestations by Rhipicephalus microplus, the cattle tick, cause enormous losses to health and animal production. Ticks induce immune response in their hosts; therefore their immunobiological control is feasible. The available anti-tick vaccines display variable efficacy and short-lived, encouraging the search for new protective antigens. The identification of important genes in tick parasitism may indicate protective antigens useful to compose an anti-tick vaccine. We have developed and tested so far four recombinant salivary antigens as a multicomponent anti-tick vaccine in tick-susceptible bovines (Holstein breed). The challenge with R. microplus larvae displayed that tick infestation in vaccinated bovines was significantly reduced. In order to elucidate the molecular mechanisms tri

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Bos taurus

SUBMITTER: Sandra Regina Maruyama 

PROVIDER: E-MTAB-8022 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress