Detecting lung tumors from circulating microRNA profiles

ABSTRACT: We aimed to determine if lung cancer detection can be improved by circulating miRNAs as biomarkers. To this end, we collected blood of over 3000 individuals using PAXgene blood tubes. The individuals were diagnosed with lung cancer (LCa), a non-tumor lung disease (NTLD), another disease (OD) or were healthy controls. For every individual we determined their miRNA expression patterns. Total RNA was extracted with Qiagen PAXgene Blood miRNA Kit, labeled and hybridized with the Agilent miRNA Complete Labeling and Hyb Kit and scanned with Agilent microarray scanner system.

ORGANISM(S): Homo sapiens

SUBMITTER: Tobias Fehlmann 

PROVIDER: E-MTAB-8026 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress