Transcranial current stimulation in the sensorimotor cortex of rats alters the expression of immune-mediating genes

ABSTRACT: Transcranial direct current stimulation (tDCS) has been applied in experimental and clinical settings for more than twenty years and may facilitate rehabilitation after stroke as suggested by clinical data (Hummel et al. 2005, Sparing et al. 2009). Intriguingly, tDCS evokes various cellular effects exceeding its primary neurophysiological actions: We previously described subacute effects of tDCS on immune- and stem cells in the rat brain (Rueger et al. 2012, Keuters et al. 2015, Pikhovych et al. 2016, Braun et al. 2016). However, the effects of tDCS on immune-mediating genes have not yet been investigated. To investigate the more immediate effects of tDCS regulating those cellular responses, we treated rats with a single session of either anodal or cathodal tDCS, and analyzed the gene exp

ORGANISM(S): Rattus norvegicus

SUBMITTER: Monika Rabenstein 

PROVIDER: E-MTAB-8318 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress