Deletion of LOX-1 has protective effects on ischemic brain damage in the genetic background of stroke-prone spontaneously hypertensive rat

ABSTRACT: To explore the impact of oxidized low density lipoprotein receptor 1 (Olr1 aka LOX-1) gene on stroke, we newly generate a LOX-1 deficient strain of the genetic background of stroke-prone spontaneously hypertensive rat (SHRSP). We explored circulatory miRNAs as diagnostic biomarkers for cerebral ischemic injury by microarray analysis in related rat strains.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Norihiro Kato 

PROVIDER: E-MTAB-8389 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress