Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

15 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Illumina Omni2.5-Octo BeadChip data from 55 Fulani individuals from Ziniare, Burkina Faso and 7 Czechs & Slovaks collected in Prague, Czech Republic.

ABSTRACT: Genotype data from 55 Fulani individuals from Ziniare, Burkina Faso and 7 Czechs & Slovaks collected in Prague, Czech Republic The data was typed in Illumina Omni2.5-Octo BeadChip.

ORGANISM(S): Homo sapiens

SUBMITTER: Carina Schlebusch

PROVIDER: E-MTAB-8434 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Genomic variation in Mozambique and Angola: Contribution to the Bantu Expansion

Project description:We seek to investigate the genetic relationships between different Bantu-speaking populations and the migratory routes they followed during various phases of the Bantu expansion. Genomic and whole genome amplified DNA were genotyped on the Illumina InfiniumOmni2.5Exome-8v1.3 array. For quality control filtering, we used the PLINK v1.9 software and custom scripts.

2019-11-24 | E-MTAB-8450 | biostudies-arrayexpress

Genotyping of 75 individuals from the Afrikaner population of South Africa

Project description:The Afrikaner population of South Africa are the descendants of European colonists who started to colonize the Cape of Good Hope in the 1600s. In the early days of the colony, mixed unions between European males and non-European females gave rise to admixed children who later became incorporated into either the Afrikaner or the “Coloured" populations of South Africa. Differences in ancestry, social class, culture, sex ratio and geographic structure led to distinct characteristic admixture patterns in the Afrikaner and Coloured populations. The Afrikaner population has a predominant European composition, whereas the Coloured population has more diverse ancestries. Genealogical records previously estimated the contribution of non-Europeans into the Afrikaners to be between 5.5%-7.2%. NB two individuals withdrew consent so this data contains only 75 individuals as compared to the 77 cited in the article.

2020-01-28 | E-MTAB-8757 | biostudies-arrayexpress

Genotyping of 327 individuals from 14 populations across the Sahel/Savannah belt that were genotyped on the Illumina H3Africa Consortium Array.

Project description:The Sahel/Savannah belt harbours diverse populations with different demographic histories and different subsistence patterns. However, populations from this large African region are notably under-represented in genomic research. To investigate the population structure and adaptation history of populations from the Sahel/Savannah space, we generated dense genome-wide genotype data of 327 individuals—comprising 14 ethnolinguistic groups, including ten previously unsampled populations. DNA samples were genotyped on the Illumina H3Africa Consortium Array (BeadChip type: H3Africa_2017_20021485_A2; designed for SNP-genotyping of 2,267,346 SNPs) at the SNP&SEQ Technology Platform, NGI/SciLifeLab Genomics (Sweden). Reference: Demographic and Selection Histories of Populations Across the Sahel/Savannah Belt. Fortes-Lima C, Tříska P, Čížková M, Podgorná E, Diallo MY, Schlebusch CM, Černý V. Molecular Biology and Evolution 2022 39(10):msac209. doi: 10.1093/molbev/msac209. PMID: 36173804 .

2022-10-31 | E-MTAB-12243 | biostudies-arrayexpress

Illumina Omni2.5-Octo BeadChip data from 50 Khoe-San individuals from Xade and 1 from Ghanzi in Botswana.

Project description:Genotype data from 50 Khoe-San individuals from Xade and 1 individual from Ghanzi in Botswana. The data was typed in Illumina Omni2.5-Octo BeadChip.

2019-04-26 | E-MTAB-7813 | biostudies-arrayexpress

Fibroblasts prepared from stroma of basal cell carcinoma in comparison to normal dermal fibroblasts

Project description:Adult tissue stem cells are known to participate in cancer formation. Indeed, cells exhibiting markers of embryonic stem cells such as Oct-4 and Nanog were detected in some malignant tumors. In this study we demonstrated that stromal cells prepared from the basal cell carcinoma are able to induce expression of embryonic stem cell markers such as the Oct-4, Nanog and Sox-2 in mouse 3T3 fibroblasts. These stem cell-like elements have the differentiation potential similar to mesenchymal stem cells. They are also able to induce expression of Oct-4 and Nanog in the human hair follicle keratinocytes. Employing the microarray technology, the role of growth factors such as IGF-2, FGF-7, leptin, NGF and TGF-_ produced by stromal fibroblasts was established to be responsible for the biological activity of the fibroblasts.

2011-11-02 | E-MTAB-272 | biostudies-arrayexpress

Transcription profiling of human fibroblasts from the stroma of squamous cell carcinoma and normal dermal fibroblasts

Project description:Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes. Epithelial-mesenchymal interaction between stromal fibroblasts and cancer cells influences the functional properties of tumor epithelium including the tumor progression and spreading. We compared fibroblasts prepared from stroma of squamous cell carcinoma and normal dermal fibroblasts concerning their biological activity towards normal keratinocytes assessed by immunocytochemistry and profiling of gene activation for growth factors/cytokines by microarray chip technology. IGF-2 and BMP-4 were determined as candidate factors responsible for tumor associated fibroblast activity that influence normal epithelia. This effect was confirmed by addition of recombinant IGF-2 and BMP4 respectively to the culture medium. This hypothesis was also verified by inhibition experiments where blocking antibodies were employed in medium conditioned by cancer associated fibroblast. Presence of these growth factors was also detected in tumor samples.

2009-12-31 | E-MTAB-97 | biostudies-arrayexpress

Epigenome-wide DNA methylation profiling in CD4+ and CD8+ T cells from patients with multiple sclerosis and healthy controls followed during (1st, 2nd and 3rd trimester) and after pregnancy.

Project description:Patient with multiple sclerosis improves during pregnancy while temporarily worsening post-partum. The reasons behind the disease modulation during pregnancy remain unknown. In this study, we have investigated the effect of pregnancy on circulating CD4+ and CD8+ T cells from patients with multiple sclerosis and healthy controls to gain a deeper understanding why patients with multiple sclerosis improves during pregnancy. We assessed epigenome-wide DNA methylation in CD4+ and CD8+ T cells obtained during (1st, 2nd and 3rd trimester) and after pregnancy (6 weeks post-partum), using the Infinium MethylationEPIC 850K array.

2023-09-23 | E-MTAB-12250 | biostudies-arrayexpress

Transcription profiling by array of rat liver from recombinant inbred strains derived from BN and SHR rats

Project description:We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.

2011-07-12 | E-MTAB-323 | biostudies-arrayexpress

Transcription profiling by array of rat aorta from recombinant inbred strains derived from BN and SHR rats

Project description:We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.

2011-07-12 | E-MTAB-322 | biostudies-arrayexpress

Transcription profiling of skeletal muscle tissue from spontaneously hypertensive rats and normotensive rats in a set of recombinant inbred strains

Project description:We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.

2008-04-15 | E-TABM-458 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data