Transcriptome analysis of human primary fibroblasts treated with 250µM HU versus untreated primary fibroblats

ABSTRACT: We analyzed the transcription response of human primary fibroblasts exposed (3 days) to a non blocking dose of HU (250µM). This dose of HU generates a replication stress, but the canonical DDR is not fully activated and the cells still proliferate and synthetize DNA; however, cells respond to such low stress (L-stress). Here we made a global analysis of the transcription response of cells to such low replication stress (non blocking).

ORGANISM(S): Homo sapiens

SUBMITTER: Bernard Lopez 

PROVIDER: E-MTAB-8605 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress