Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells

ABSTRACT: Syncytial skeletal muscle cells contain hundreds of nuclei in a shared cytoplasm. Using single nucleus RNA-sequencing (snRNAseq) of isolated nuclei from muscle fibers, we investigated nuclear heterogeneity and transcriptional dynamics in uninjured and regenerating muscle.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Vedran Franke 

PROVIDER: E-MTAB-8623 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress