Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Comparative gene expression profiling of Drosophila primary neuronal cultures expressing or not the human Tau0N4RWT protein


ABSTRACT: Deciphering the pathophysiological mechanisms that lead from the alteration of human Tau biology to neuronal death in tauopathies including Alzheimer's disease (AD), fronto-temporal dementia with parkinsonism linked to chromosome 17 (FTDP-17), Pick's disease (PiD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) depends notably on the identification of Tau cellular partners and a better understanding of Tau functions. In this aim, we performed gene expression profiling to identify upregulated and downregulated genes in response to ectopic induced expression for 3 days of human Tau0N4RWT protein in Drosophila primary neuronal cultures from Elav-GAL4GS larval brains.

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Sebastien FEUILLETTE 

PROVIDER: E-MTAB-8712 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2022-03-01 | PXD025301 | Pride
2024-04-08 | GSE255904 | GEO
2024-04-08 | GSE255902 | GEO
2020-02-14 | PXD016862 | Pride
2021-09-16 | E-MTAB-5742 | biostudies-arrayexpress
2018-08-01 | GSE106075 | GEO
2018-08-01 | GSE104013 | GEO
2023-09-25 | GSE242694 | GEO
2018-07-04 | GSE115606 | GEO
2023-05-17 | GSE226624 | GEO