Gene expression differences between striatum of vehicle- or L-DOPA-treated FRL and FSL rats

ABSTRACT: Total RNA was extracted from the striatum of vehicle- or L-DOPA-treated FRL and FSL rats. After quality control, RNA samples were submitted to the Gene Expression Service Workflow of Roche NimbleGen, which included hybridization with a Roche NimbleGen Rat Gene Expression 12x135K Array (Design Name 100718_Rat_HX12_expr), array scanning, data extraction and processing. Normalized gene expression data (\\"Normalized Calls\\") provided by Roche NimbleGen were analyzed using ANAIS [Simon and Biot, Bioinformatics 2010 Oct; 26(19):2468-9] via the \\"Norm genes\\" function. Genes were considered differentially expressed if their transcript abundance (scanned signal intensity) was ≥1.5-fold higher or lower in at least one experimental group compared to striatum of vehicle-treated FRL rats. The resu

ORGANISM(S): Rattus rattus

SUBMITTER: per svenningsson 

PROVIDER: E-MTAB-8822 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress