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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptional start site mapping of P14 WT and P14 Tbpl2-/- mutant mouse oocytes

ABSTRACT: We used SLIC-CAGE to map transcriptional start sites (TSSs) of P14 WT and P14 Tbpl2-/- mutant mouse oocytes. Comparison of WT and Tbpl2-/- oocytes demonstrates that Tbpl2 guides transcriptional start site selection in the growing oocyte. This TSS selection is different compared to the canonical somatic type of TSS selection and depends on TATA-like elements as core promoter motifs, recognised by Tbpl2.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Nevena Cvetesic

PROVIDER: E-MTAB-8866 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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