Transcriptome profiling of NGLY1 deficient K562 cells

ABSTRACT: The data includes a transcriptome analysis of K562 cell lines in which the gene N-glycanase 1 (NGLY1) was mutated in exon 1 and/or exon 3 to include loss of function mutations as described in Mueller and Jakob et al, 2020. The data were used in conjunction with whole proteome MS/MS experiments to show a gene expression profile consistent with NGLY1 deficiency, a human disease. The experiments demonstrate the wide ranging effect of the loss of NGLY1 on a cellular system.

ORGANISM(S): Homo sapiens

SUBMITTER: Charles Girardot 

PROVIDER: E-MTAB-8876 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress