NuRD-mediated gene repression in mouse embryonic stem cells

ABSTRACT: To obtain a global view of NuRD-mediated transcriptional regulation, gene expression profiles of wild-type and Mbd3-null ES cells were compared by microarray analysis. In the absence of Mbd3, which encodes a core structural component of NuRD, the complex does not form and embryonic development stalls at the implantation stage.

ORGANISM(S): Mus musculus

SUBMITTER: Paul Bertone 

PROVIDER: E-MTAB-889 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress