Transcription profiling by array of rat spinal cord from DA, PVG and congenic strains following ventral root avulsion(VRA)

ABSTRACT: The current experiment is a continuation of a previous study (E-MTAB-303) where spinal cords from a F2 (DAxPVG) intercross exposed to ventral root avulsion was studied. The F2 experiment revealed specific genetic regions of interest. Now, congenic lines, i.e. DA rats containing small inserts of PVG DNA fragments, have been developed, clinically evaluated and selected to study further with transcriptional profiling in order to understand the genetic pathways underlying the observed differential clinical phenotypes, determined by the small DNA inserts.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Rickard Lindblom 

PROVIDER: E-MTAB-920 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress