Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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CDNA microarray Analysis of human iPSC-derived mesodermal progenitors treated with CHIR99021 compared to controls


ABSTRACT: The aim of this study was to unravel the effects of an initial WNT/β-catenin pulse on the in vitro differentiation of human iPSCs towards mesodermal progenitors and subsequent specification of chondrocytes. Therefore, mesodermal progenitors were generated from hiPSCs according to standard protocol (ctrl) or treated with 5 µM WNT/β-catenin agoinst CHIR99021 for 24h. To understand the long-term effects of short-initial WNT pulse on mesodermal differentiation, the global gene expression profile of day 14 mesodermal progenitors was compared.

ORGANISM(S): Homo sapiens

SUBMITTER: Ursula Kreuser 

PROVIDER: E-MTAB-9226 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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