Decorin protects cardiac myocytes against simulated ischemia/reperfusion injury

ABSTRACT: Primary cardiac myocytes isolated from neonatal Wistar rats were cultured and simulated ischemia/reperfusion injury were conducted on them in the presence or absence of decorin. Decorin is a small leucin-rich proteoglycan, which has a cardiocytoprotective effect. The underlaying mechanism of this cardiocytoprotective phenomenon is unknown, therefore our aim was to investigate the changes in the mRNA expression between the decorin (3nM) treated and vehicle-treated control cells.

INSTRUMENT(S): NextSeq 550

ORGANISM(S): Rattus norvegicus

SUBMITTER: Kamilla Gömöri 

PROVIDER: E-MTAB-9325 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress