Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcriptome of Yarrowia lipolytica strain E150 delta-Ku70 on glucose


ABSTRACT: batch culture of Yarrowia lipolytica strain E150 delta-Ku70

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Yarrowia lipolytica

SUBMITTER: Cecile Neuvéglise 

PROVIDER: E-MTAB-940 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Alternative splicing regulates targeting of malate dehydrogenase in Yarrowia lipolytica.

Kabran Philomène P   Rossignol Tristan T   Gaillardin Claude C   Nicaud Jean-Marc JM   Neuvéglise Cécile C  

DNA research : an international journal for rapid publication of reports on genes and genomes 20120224 3


Alternative pre-mRNA splicing is a major mechanism contributing to the proteome complexity of most eukaryotes, especially mammals. In less complex organisms, such as yeasts, the numbers of genes that contain introns are low and cases of alternative splicing (AS) with functional implications are rare. We report the first case of AS with functional consequences in the yeast Yarrowia lipolytica. The splicing pattern was found to govern the cellular localization of malate dehydrogenase, an enzyme of  ...[more]

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