Transcription profiling by array of breast cancer distant metastasis based on outcome over time and identification of pathway activities of late relapse

ABSTRACT: Previous reports have described the use of microarrays to assess the molecular classification of human breast cancers and defined new subgroups based on gene expression that are relevant to patient management through their ability to predict metastatic relapse and survival relapse. However, different mechanisms may be associated with the development of early and late distant metastases. With the hypothesis that tumors may lead to early or distant metastases based on their intrinsic biological initial features. We aimed at defining molecular profiles for several subgroups of patients based on their outcome over time. Breast primary tumors were selected from retrospective series of patients with frozen material available. These series include patients of all ages, LN- and LN+; Estrogen or Pr

ORGANISM(S): Homo sapiens

DISEASE(S): normal

SUBMITTER: Philippe DESSEN 

PROVIDER: E-MTAB-949 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress