RNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.

ABSTRACT: Zbtb2 mutant mouse embryonic stem cells are defective in exiting the pluripotent state. To determine the transcriptional changes underlying this phenotype we performed RNA-seq of wildtype and Zbtb2 mutant cells; in the naïve pluripotent state in 2iLIF, and after 24h and 48h of exposure to SerumLIF and epiblast-like cell (EpiLC) differentiation conditions.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Joerg Betschinger 

PROVIDER: E-MTAB-9797 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress