Dataset Information
Transcription profiling of 165 human primary breast carcinomas and 15 recurred tumors to investigate expression profiles in relation to the risk of developing local recurrence after breast conserving therapy
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): no local recurrence
SUBMITTER: bas kreike
PROVIDER: E-NCMF-24 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Local recurrence after breast-conserving therapy in relation to gene expression patterns in a large series of patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090526 12
<h4>Purpose</h4>The majority of patients with early-stage breast cancer are treated with breast-conserving therapy (BCT). Several clinical risk factors are associated with local recurrence (LR) after BCT but are unable to explain all instances of LR after BCT. Here, gene expression microarrays are used to identify novel risk factors for LR after BCT.<h4>Experimental design</h4>Gene expression profiles of 56 primary invasive breast carcinomas from patients who developed a LR after BCT were compar ...[more]
