Dataset Information
Transcription profiling of human breast cancer cell line comparing RNA of spheres with co-responding parental cell line
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Tania Margarido
PROVIDER: E-NCMF-25 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Mammosphere-derived gene set predicts outcome in patients with ER-positive breast cancer.
The Journal of pathology 20090701 3
Tumourigenic subpopulations with stem cell-like features have been identified in breast tumours and breast cancer cell lines. The hormone receptor status, molecular characteristics and clinical significance of these cells are still matters of debate. Enrichment for tumourigenic cells without the requirement of surface markers can be achieved by the in vitro mammosphere culture assay. Here we compared the hormone receptor status and genome-wide gene expression profiles of mammospheres derived fro ...[more]
