Transcription profiling of C. elegans with activated let-60 Ras

ABSTRACT: In Caenorhabditis elegans, let-60 Ras controls many cellular processes, such as differentiation of vulval epithelial cells, function of chemosensory neurons, and meiotic progression in the germ line. Although much is known about the let-60 Ras signaling pathway, relatively little is understood about the target genes induced by let-60 Ras signaling that carry out terminal effector functions leading to morphological change. We have used DNA microarrays to identify 708 genes that change expression in response to activated let-60 Ras.

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Beatrice Romagnolo 

PROVIDER: E-SMDB-1398 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress