Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling analysis of yeast membrane bound polysomes vs free polysomes


ABSTRACT:

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Max Diehn 

PROVIDER: E-SMDB-156 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Large-scale identification of secreted and membrane-associated gene products using DNA microarrays.

Diehn M M   Eisen M B MB   Botstein D D   Brown P O PO  

Nature genetics 20000501 1


Membrane-associated and secreted proteins are an important class of proteins and include receptors, transporters, adhesion molecules, hormones and cytokines. Although algorithms have been developed to recognize potential amino-terminal membrane-targeting signals or transmembrane domains in protein sequences, their accuracy is limited and they require knowledge of the entire coding sequence, including the N terminus, which is not currently available for most of the genes in most organisms, includ  ...[more]

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