Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of yeast elutriation time series (Spellman et al.)

ABSTRACT: Reproduced from P. T. Spellman, G. Sherlock, M. Q. Zhang, V. R. Iyer, K. Anders, M. B. Eisen, P. O. Brown, D. Botstein and B. Futcher, "Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization," Molecular Biology of the Cell 9 (12), pp. 3273--3297 (December 1998).

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Paul Spellman 

PROVIDER: E-SMDB-1887 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms.

Alter Orly O   Brown Patrick O PO   Botstein David D  

Proceedings of the National Academy of Sciences of the United States of America 20030311 6

We describe a comparative mathematical framework for two genome-scale expression data sets. This framework formulates expression as superposition of the effects of regulatory programs, biological processes, and experimental artifacts common to both data sets, as well as those that are exclusive to one data set or the other, by using generalized singular value decomposition. This framework enables comparative reconstruction and classification of the genes and arrays of both data sets. We illustra  ...[more]

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