Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of a complex phenotype: cord formation in Mycobacterium tuberculosis


ABSTRACT: Tuberculosis (2004) 84, 188196 (www.elsevierhealth.com/journals/tube),Comparative expression studies of a complex phenotype: cord formation in Mycobacterium tuberculosis,Qian Gao, Katharine Kripke, Zuhre Arinc, Martin Voskuil, Peter Small

ORGANISM(S): Mycobacterium tuberculosis

SUBMITTER: Janos Demeter 

PROVIDER: E-SMDB-2867 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparative expression studies of a complex phenotype: cord formation in Mycobacterium tuberculosis.

Gao Qian Q   Kripke Katharine K   Arinc Zuhre Z   Voskuil Martin M   Small Peter P  

Tuberculosis (Edinburgh, Scotland) 20040101 3-4


The aggregation of mycobacteria into structures known as cords is an intrinsic property of the human tubercle bacillus. This property is thought to be determined by the lipid composition of the bacterial cell surface and may contribute to the virulence of the organism. Using microarray technology, we compared the pattern of gene expression of H37Rv, a virulent, cording strain of Mycobacterium tuberculosis, with H37Ra, an avirulent, non-cording strain derived from the same original patient isolat  ...[more]

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