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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Mycobacterium tuberculosis 12 clinical isolates

ABSTRACT: Protocol Name

ORGANISM(S): Mycobacterium tuberculosis

SUBMITTER: Qian Gao

PROVIDER: E-SMDB-2885 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene expression diversity among Mycobacterium tuberculosis clinical isolates.

Gao Qian Q Kripke Katharine E KE Saldanha Alok J AJ Yan Weihong W Holmes Susan S Small Peter M PM

Microbiology (Reading, England) 20050101 Pt 1

Intraspecies genetic diversity has been demonstrated to be important in the pathogenesis and epidemiology of several pathogens, such as HIV, influenza, Helicobacter and Salmonella. It is also important to consider strain-to-strain variation when identifying drug targets and vaccine antigens and developing tools for molecular diagnostics. Here, the authors present a description of the variability in gene expression patterns among ten clinical isolates of Mycobacterium tuberculosis, plus the labor ...[more]

PMID: 15632420

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