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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomic hybridization of mouse adapted strains of Helicobacter pylori

ABSTRACT: Microarray based comparative genomic hybridization of mouse adapted strains: 10700 pre-mouse SS1, SS1(A.L.)Sydney strain obtained directly from Adrian Lee, NSH79 Salama lab strain labeled as SS1-now know distinct, G27 obtained from Antonello Covacci. Genomic DNA from est strain (Cy5), genomic DNA from reference strains used for array fabrication (equimolar mix of 26695 and J99 genomic DNA)

ORGANISM(S): Helicobacter pylori

SUBMITTER: Janos Demeter

PROVIDER: E-SMDB-3902 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Identification of Helicobacter pylori genes that contribute to stomach colonization.

Baldwin David N DN Shepherd Benjamin B Kraemer Petra P Hall Michael K MK Sycuro Laura K LK Pinto-Santini Delia M DM Salama Nina R NR

Infection and immunity 20061113 2

Chronic infection of the human stomach by Helicobacter pylori leads to a variety of pathological sequelae, including peptic ulcer and gastric cancer, resulting in significant human morbidity and mortality. Several genes have been implicated in disease related to H. pylori infection, including the vacuolating cytotoxin and the cag pathogenicity island. Other factors important for the establishment and maintenance of infection include urease enzyme production, motility, iron uptake, and stress res ...[more]

PMID: 17101654

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Mouse adapted strain CGH

Project description:Microarray based comparative genomic hybridization of mouse adapted strains: 10700 pre-mouse SS1, SS1(A.L.)Sydney strain obtained directly from Adrian Lee, NSH79 Salama lab strain labeled as SS1-now know distinct, G27 obtained from Antonello Covacci. Genomic DNA from est strain (Cy5), genomic DNA from reference strains used for array fabrication (equimolar mix of 26695 and J99 genomic DNA) An all pairs experiment design type is where all labeled extracts are compared to every other labeled extract. Keywords: all_pairs

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