Transcription profiling of cynomolgus macaques sequential blood samples infected with Ebola virus

ABSTRACT:

Title: Ebola-infected non-human primates - PBMCs

Summary: Infection with Ebola virus (EBOV) causes a fulminant and often fatal hemorrhagic fever. In order to improve our understanding of EBOV pathogenesis and EBOV-host interactions we have examined the molecular features of EBOV infection in vivo. Using self-spotted cDNA microarrays, we analyzed genome-wide host expression patterns in sequential blood samples from nonhuman primates (NHP) infected with EBOV.

Overall Design: Ebola infection of non-human primates (cynomolgus macaques). We took sequential samples of peripheral blood mononuclear cells (PBMC) from 15 cynomolgus macaques infected intramuscularly with 1000 plaque forming units (PFUs) of EBOV

ORGANISM(S): Macaca fascicularis

SUBMITTER: Janos Demeter 

PROVIDER: E-SMDB-4098 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress