Transcription profiling by array of Atlantic salmon fed genetically modified Bt-maize or non-modified parental maize

ABSTRACT: This study was conducted to follow up on apparent differences in growth, relative organ sizes, cellular stress and immune function in Atlantic salmon fed genetically modified (GM) Bt-maize compared to the non-modified parental maize line. Gene expression profiling on the distal intestinal segment and liver were performed by the cGRASP 16K salmonid cDNA microarray. Analysis of the intestinal microarray data revealed nearly 500 differentially regulated genes with a false discovery rate of zero, despite modest fold differences (average 2.4 for the down-regulated and 1.7 for the up-regulated genes). However, nine out of ten genes were found not to be significantly different when followed up by quantitative polymerase chain reaction (qPCR), but direction and magnitude of the change was generall

ORGANISM(S): Salmo salar

SUBMITTER: Monica Sanden 

PROVIDER: E-TABM-1056 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress