Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Cancer with unknown primary prediction


ABSTRACT: MicroRNA expression data (Agilent miRNA microarray v.2) obtained for 101 FFPE samples of primary and metastatic tumors.

ORGANISM(S): Homo sapiens

DISEASE(S): cancer

SUBMITTER: Manuela Ferracin 

PROVIDER: E-TABM-1135 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


Cancer of unknown primary (CUP) represents a common and important clinical problem. There is evidence that most CUPs are metastases of carcinomas whose primary site cannot be recognized. Driven by the hypothesis that the knowledge of primary cancer could improve patient's prognosis, we investigated microRNA expression profiling as a tool for identifying the tissue of origin of metastases. We assessed microRNA expression from 101 formalin-fixed, paraffin-embedded (FFPE) samples from primary cance  ...[more]

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