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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of 51 human breast cancer cell lines

ABSTRACT: We measured baseline gene expression profiles for a panel of 51 breast cancer cell lines using the Affymetrix U133A array.

ORGANISM(S): Homo sapiens

SUBMITTER: paul spellman

PROVIDER: E-TABM-157 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

tRNA over-expression in breast cancer and functional consequences.

Pavon-Eternod Mariana M Gomes Suzanna S Geslain Renaud R Dai Qing Q Rosner Marsha Rich MR Pan Tao T

Nucleic acids research 20091101 21

Increased proliferation and elevated levels of protein synthesis are characteristics of transformed and tumor cells. Though components of the translation machinery are often misregulated in cancers, what role tRNA plays in cancer cells has not been explored. We compare genome-wide tRNA expression in cancer-derived versus non-cancer-derived breast cell lines, as well as tRNA expression in breast tumors versus normal breast tissues. In cancer-derived versus non-cancer-derived cell lines, nuclear-e ...[more]

PMID: 19783824

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